admsc growth medium bullet kit (Lonza)
Structured Review

Admsc Growth Medium Bullet Kit, supplied by Lonza, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/admsc+growth+medium+bullet+kit/pmc06826628-38-14-20?v=Lonza
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Mesenchymal Cells Support the Oncogenicity and Therapeutic Response of the Hedgehog Pathway in Triple-Negative Breast Cancer"
Article Title: Mesenchymal Cells Support the Oncogenicity and Therapeutic Response of the Hedgehog Pathway in Triple-Negative Breast Cancer
Journal: Cancers
doi: 10.3390/cancers11101522
Figure Legend Snippet: Mesenchymal cells modulate the effect of Hedgehog (Hh) signaling. ( A , B ) Proliferation analysis of 5-ethynyl-2’-deoxyuridine (EdU)+ MDA-MB-468 and 184B5 cells co-cultured with adipose mesenchymal stem cells (ADMSC) treated with Sonic hedgehog (SHH)-ligand and Hh inhibitors for 96 h. Significance was determined via Student’s t -test, * p < 0.05. ( C ) Expression levels of glioma associated oncogene family zinc finger 1 ( GLI1 ), patched1 ( PTCH1 ) and Smoothened ( SMO ) genes relative to GAPDH at 24 h post-treatment. ( D , E ) Tumor growth curves in xenografted tumors composed by MDA-MB-468 + ADMSC +/− SHH-ligand. Daily dosage with NVP or Vehicle during the last four weeks. Data show the average mean +/− SEM of nine mice per treatment. Significance was determined via ANOVA analysis comparing Vehicle (D) or SHH (E) with NVP, * p < 0.05, ** p < 0.01, **** p < 0.0001. F ) Expression levels of GLI1 , PTCH1 , and SMO relative to GAPDH in xenografted tumors using human and mouse-specific primers. Data represent mean +/− SEM of six mice per condition. No significant differences were observed by Student’s t -test. ( G , H ) Percentage of mice with visible metastases. Significance was determined by Fisher’s exact test, * p < 0.05.
Techniques Used: Cell Culture, Expressing